Allergic hypersensitivity reactions w/ skin reactions, urticaria (nettle rash), exanthem or shock. Neuropathies when taken for >6 mth. GI disorders eg, nausea.
Drug Interactions
Concomitant use w/ pyridoxine antagonists (eg, hydralazine, INH, D-penicillamine, cycloserine), alcohol or oestrogen-containing OCs over a long time may lead to vit B6 deficiency. Thiamine is deactivated by 5-fluorouracil. Vit B6 may weaken the effect of L-dopa.
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